Qwo® Cellulite Injectable


Cellulite is a common concern for many women. Over 90% of women are affected by cellulite within their lifetime. A healthy diet and frequent, regular exercise do not improve the appearance of cellulite and topical products on the market are ineffective or the results are short lived. We now offer an injectable therapy called Qwo®, which addresses cellulite at its root cause. Qwo® is the first and currently only FDA- approved injectable for the permanent reduction of moderate to severe cellulite in the buttocks of adult women.

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Cellulite are dimples that occur due to three reasons: thinning of skin over time, enlargement of fat cells which push against the skin, and fibrous bands under the skin’s surface which thicken and cause tension. A healthy diet and muscle-strengthening exercises, in general, do not effectively address these physiologic changes and do not significantly improve the appearance of cellulite. Liposuction, commonly used for body contouring and to get rid of bothersome deposits of fat, is also ineffective in the treatment of cellulite. Qwo® targets the structural cause of cellulite.



Qwo® is made from enzymes called collagenases. These enzymes target the structural cause of cellulite under the skin where cellulite starts. It releases the fibrous bands which in turn redistributes fat cells and it also stimulates the growth of new collagen. This leads to a smoother appearance of the treated skin.

How quickly are results seen and how many treatments are needed?

Results from Qwo® injectable can be seen in less than 3 months. Three treatments are spaced three weeks apart. Dimples are identified and Qwo® injectable is delivered to each cellulite dimple through a small gauge needle. No sedation is needed.


Patients can expect bruising and mild to moderate soreness in the treated areas. The treated area can be covered with clothing and there is no social downtime. Because bruising is common side-effect of injections, we recommend you complete your three Qwo® treatments, separated by 3 weeks, well before or after bikini season. We also recommend compression (in the form of a Spanx®-like garment) for a few days after treatment, as this helps decrease swelling and bruising.

Who is a candidate for Qwo® ?

A thorough consultation is recommended prior to treatment. Ideal candidates are in good health and not taking prescription blood thinning medications. Candidates must be at least 18 years of age with moderate to severe cellulite in the buttock region. Allergies to any collagenase enzyme or to the ingredients in Qwo® or active infections in the treatment area are contraindications to receiving treatment.


Qwo® is a minimally invasive and permanent treatment for cellulite that generally provides results in as little as 10 weeks and 3 treatment sessions. It has been tested on over 1,800 women and has demonstrated safety and efficacy in reducing the appearance of cellulite.

What if there is cellulite and also skin laxity?

While Qwo® treats cellulite dimples, skin laxity (or loose skin) is another bothersome feature that can develop with age, weight changes and pregnancy. This is also something that can’t be fixed by a healthy diet and exercise regimen. Morpheus8 radiofrequency microneedling can help improve the appearance of loose skin and texture.



Actual patient. Unretouched photos taken before QWO, and 28 days after final treatment. Individual results may vary.

Women in clinical trials with an average age of 47 received 3 treatments of QWO, 21 days apart. QWO may cause serious side effects including allergic (hypersensitivity) reactions, including anaphylaxis, and injection site bruising.


Do not receive if you are allergic to collagenase or to any of the ingredients in QWO, or have an active infection in the treatment area.

Qwo® Cellulite Injectable


Do not receive QWO if you: are allergic to collagenase or to any of the ingredients in QWO, or have an active infection at the treatment area.

QWO may cause serious side effects, including:

  • Allergic (hypersensitivity) reactions, including anaphylaxis. Call your healthcare provider right away if you have hives, trouble breathing, low blood pressure, swollen face, chest pain, dizziness or fainting after receiving QWO;
  • Injection site bruising

Before receiving QWO, tell your healthcare provider if you:

  • have a bleeding problem
  • are pregnant or may become pregnant, nursing or plan to nurse. You and your healthcare provider should decide if you will receive QWO or breastfeed.

Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins and herbal supplements. Especially tell your healthcare provider if you take a medicine that prevents the clotting of your blood (antiplatelet or anticoagulant).

The most common side effects of QWO include: injection site bruising, pain, areas of hardness, itching, redness, discoloration, swelling and warmth in the treatment area.

These are not all the possible side effects of QWO. Call your healthcare provider for medical advice about side effects. You are encouraged to report side effects of prescription drugs to the FDA at www.fda.gov/medwatch or 1-800-FDA-1088.

Click for Full Prescribing Information, including Patient Information for QWO.

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